Primary Cervico-Vaginal B-cell Lymphoma with Immunohistochemical Confi rmation: A Case Study

Non-Hodgkin’s lymphoma (NHL) involving lower female genital tract is a rare event. Described presenting clinical symptoms in a literature in these patients are vaginal discharge and bleeding. Here with the report, a case of primary cervico-vaginal lymphoma in an old lady presenting with utero-vaginal (UV) prolapse. On clinical examination, there was second degree UV prolapse. Pelvic ultrasound showed a large hypo echoic mass involving the vagina with increased vascularity. To our surprise the sections from diffusely thickened vagina wall revealed high-grade round cell tumor which was diagnosed as NHL (B-cell type) by immunohistochemistry. To confi rm primary vaginal involvement detailed clinical, radiological, and hematological examination was performed. The management of this disease is not well-defi ned in the literature. In our case, post-hysterectomy, no further treatment was offered to the patient; on 18 months follow-up she is doing well with no complaints.